[PAGID] PID related tumors

[notarang at med.unibs.it]

Dear Andy:

here are a few examples of non-hematopietic tumors in PID:

Patients with ataxia-telangiectasia are at high risk for a variety of
tumors(including skin, breast, and ovarian-testicular) because of radiosensitivity.
Patients with CD40 ligand deficiency are at high risk for liver/biliary duct and
gastrointestinal (PNET) tumors. 

Luigi D. Notarangelo



> What is the feeling out there as to malignancies, other than hematopoetic
> cancers (e.g. lymphoma, leukemias) and thymoma that are clearly increased in
> PID; 
> 
> I'd love to get the impute from a lot of you on this
> 
> ? Skin	Basal Cell
> 	Melanoma
> 	Squamous Cell
> 
> ?GI	Gastric (assoc with atrophic gastritis in CVID)
> 
> 
> ? Others
> 	Cervix ?
> 	Breast?
> 	Testicular?
> 	Kidney
> 	Prostate?
> 	Colon?
> 
> Thanks 
> 
> Andy Saxon, MD
> UCLA
> 
> 
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