[PAGID] DiGeorge and GVHD

[Kathleen E. Sullivan]

As you well know, the survival for SCID patients with transfusion  
associated GVHD is extremely poor and the mechanism is roughly the  
same here.  We did have one SCID survivor after transfusion  
associated GVHD.  The strategy was to take him for transplant and   
fully ablate as soon as possible.  During the brief interval prior to  
transplant we had him on very sturdy immunosuppression.  These days,  
I might think about Campath as an option.

kate

Kathleen E. Sullivan MD PhD
Chief, Division of Allergy and Immunology
Associate Professor of Pediatrics
The Children's Hospital of Philadelphia
(p) 215-590-1697
(f) 267-426-0363


On Feb 9, 2007, at 9:51 AM, James Moy wrote:


> Unfortunately, most likely transfusion related.  Our A/I service  

> was consulted after the initial presentation of GVHD.

>

> James N. Moy, M.D.

> Chief,

> Division of Allergy and Immunology

> Department of Pediatrics

> Stroger Hospital of Cook County

>

> Associate Professor,

> Director,

> Section of Allergy and Immunology

> Department of Immunology/Microbiology

> Rush Medical College

>

> On Feb 8, 2007, at 12:27 PM, Kathleen E. Sullivan wrote:

>

>> As in maternal GVHD?

>>

>> Kathleen E. Sullivan MD PhD

>> Chief, Division of Allergy and Immunology

>> Associate Professor of Pediatrics

>> The Children's Hospital of Philadelphia

>> (p) 215-590-1697

>> (f) 267-426-0363

>>

>>

>> On Feb 8, 2007, at 8:19 AM, James Moy wrote:

>>

>>> What are the treatment options for a 6 week old with DiGeorge and  

>>> GVHD with skin and liver involvement?

>>>

>>> James Moy, M.D.

>>> Stroger Hospital of Cook County

>>> Chicago

>>

>


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