[PAGID] DiGeorge and GVHD

[K. Scott Baker]

Certainly if a well matched donor were available a reduced intensity
conditioning regimen may be sufficient in this situation and something to
consider.   I would agree that a transplant will be necessary.

 

K. Scott Baker, MD, MS

Pediatric Blood and Marrow Transplant Program

University of Minnesota

420 Delaware St. SE, Mayo Bldg. Room D557

Mayo Mail Code 484

Minneapolis, MN 55455

612.625.4952  FAX 612.626.1434

baker084 at tc.umn.edu

  _____  

From: pagid-bounces at list.clinimmsoc.org
[mailto:pagid-bounces at list.clinimmsoc.org] On Behalf Of James Moy
Sent: Friday, February 09, 2007 2:02 PM
To: pagid at list.clinimmsoc.org
Subject: Re: [PAGID] DiGeorge and GVHD

 

Thank you. We will begin communicating with transplantation centers
immediately.

On Feb 9, 2007, at 9:06 AM, Kathleen E. Sullivan wrote:





As you well know, the survival for SCID patients with transfusion associated
GVHD is extremely poor and the mechanism is roughly the same here. We did
have one SCID survivor after transfusion associated GVHD. The strategy was
to take him for transplant and fully ablate as soon as possible. During the
brief interval prior to transplant we had him on very sturdy
immunosuppression. These days, I might think about Campath as an option.

 

kate

 

Kathleen E. Sullivan MD PhD

Chief, Division of Allergy and Immunology

Associate Professor of Pediatrics

The Children's Hospital of Philadelphia

(p) 215-590-1697

(f) 267-426-0363





 

On Feb 9, 2007, at 9:51 AM, James Moy wrote:





Unfortunately, most likely transfusion related. Our A/I service was
consulted after the initial presentation of GVHD.

 

James N. Moy, M.D.

Chief,

Division of Allergy and Immunology

Department of Pediatrics

Stroger Hospital of Cook County

 

Associate Professor,

Director,

Section of Allergy and Immunology

Department of Immunology/Microbiology

Rush Medical College

 

On Feb 8, 2007, at 12:27 PM, Kathleen E. Sullivan wrote:





As in maternal GVHD?

 

Kathleen E. Sullivan MD PhD

Chief, Division of Allergy and Immunology

Associate Professor of Pediatrics

The Children's Hospital of Philadelphia

(p) 215-590-1697

(f) 267-426-0363





 

On Feb 8, 2007, at 8:19 AM, James Moy wrote:





What are the treatment options for a 6 week old with DiGeorge and GVHD with
skin and liver involvement?

 

James Moy, M.D.

Stroger Hospital of Cook County

Chicago

 

 

 

 

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