[PAGID] Cellcept for ITP and CVID

[Charlotte Cunningham-Rundles]

Too soon to know if the rituxan was helpful, wait a bit and see. 
takes at least a month or 6 weeks to get all the benefit. We have 
used it in the worst of the worst.  I'd hold off on cell cept for now.



>Hello,

>

>Has anyone had success using cellcept for ITP in CVID patients?  I have a

>teenager who presented a number of years ago with ITP and AIHA.  She

>fulfills the criteria for CVID and is on IVIG.  She had a recent flare in

>her ITP and failed increasing her IVIG.  She was started on prednisone and

>rituxan.  She just finished her fourth cycle of rituxan and is tapering on

>her prednisone.  She responded nicely (I think more to the steroids than the

>rituxan since the response was early and rapid) but now her platelets are

>slowly dropping.  As opposed to offering splenectomy, I was thinking of

>cellcept since I think the risk/benefit is better in general.  Thank you for

>sharing your experiences.  Chris

>

>

>Chris Seroogy, M.D.

>

>University of Wisconsin

>

>Assistant Professor

>

>Dept. of Pediatrics

>

>Mail:  H4/474 CSC, Mailstop 4108

>

>Shipping:  H4/431 CSC, Mailstop 4108

>

>600 Highland Ave.

>

>Madison, WI  53792

>

>phone: 608- 263-2652

>

>fax: 608-265-0164

>

>The information in this message (and the documents attached to it, if

>

>any) is confidential and may be legally privileged.  It is intended

>

>solely for the addressee.  Access to this message by anyone else is

>

>unauthorized.  If you are not the intended recipient, any disclosure,

>

>copying, distribution or any action taken, or omitted to be taken in

>

>reliance on it is prohibited and may be unlawful.  If you have received

>

>this message in error, please delete all electronic copies of this

>

>message (and the documents attached to it, if any), destroy any hard

>

>copies you may have created and notify me immediately by replying to

>

>this email.  Thank you.



-- 


Charlotte Cunningham-Rundles MD PhD
Professor of Medicine, Pediatrics  and Immunobiology
Mount Sinai School of Medicine
1425 Madison Ave, New York 10029
phone 212 659 9268
fax  212 987 5593
Email:  charlotte.cunningham-rundles at mssm.edu