[PAGID] PAGID posting

[Anita Gewurz]

Dear Paige,

We had a patient with Bloom syndrome (OMIM #210900) who presented  
with misdiagnosed CVID and IVIG therapy for low Igs.  The subsequent  
clinical course included laryngoesophagitis followed by oropharyngeal  
squamous cell cancer, myelodysplastic syndrome and death from  
nosocomial osteomyelitis.  The DNA helicase BLM gene mutation  
disrupts T, B and NK development and function.  I think Bloom  
syndrome could be included in your patient's DDx.

Sincerely,

Anita Gewurz MD
Section of Allergy/Immunology
Department of
      Immunology/Microbiology
Rush University Medical Center
1725 W Harrison - 117
Chicago IL 60612
TEL (312) 942-6296
FAX (312) 563-2201
EMAIL agewurz at rush.edu


On Apr 10, 2009, at 10:25 AM, Paige wickner wrote:


> Hi - I wanted to post the attached case to the list. Thank you! I  

> havent submitted a case before- so is this how it works?

> Thank you!

> Paige Wickner

> Allergy/Immunology Fellow

> Yale New Haven Hospital<case_for_PAGID.doc>


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