[PAGID] Synagis (palivizumab) in hypogamm

[Kobrynski, Lisa]

Jason
I would say that probably no one would be able to get reimbursement to use SYnagis in such a case.  The guidelines put out by the RedBook are written in granite.  So unless the child has documented lung disease (BPD, interstitial lung disease, not just asthma) and/or cyanotic heart disease it is unlikely to be used.
I have used in for some 22qDS/Digeorge patients with congenital heart disease (even non-cyanotic) who had decreased in T cell # (even with normal Igs) up to age 2 yrs.
Hope that helps.
Lisa


Lisa Kobrynski, MD, MPH
Associate Professor of Pediatrics
Division of Pulmonary, Allergy/Immunology, Cystic Fibrosis and Sleep Apnea
Emory Children's Center


-----Original Message-----
From: pagid-bounces at list.clinimmsoc.org [mailto:pagid-bounces at list.clinimmsoc.org] On Behalf Of raas0027 at umn.edu
Sent: Wednesday, October 28, 2009 4:10 PM
To: pagid at list.clinimmsoc.org
Subject: [PAGID] Synagis (palivizumab) in hypogamm


Dear colleagues,

This is somewhat related to a question posed a few weeks ago.

Who has used (or routinely uses) Synagis (palivizumab) in children [under
two years of age] who have symptomatic (recurrent upper/lower respiratory
infection) hypogammaglobulinemia [presumbably 'transient']?

Sorry for all the qualifiers - there are so many variables.

Specifically in children who are NOT on immunoglobulin replacement therapy.

If you haven't used it, have you considered it?

Thank you for your input!

Regards,

Jason



--


Jason P. Raasch, MD

Midwest Immunology Clinic
City Center Professional Building
15700 37th St NE
Suite 110
Plymouth, MN 55446

Office: 763.577.0008
FAX: 763.577.0192
raas0027 at umn.edu



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