[PAGID] XLA and Spondyoarthritis

[Church, Joseph]

Colleagues:

 

I have a 10yo with XLA and HLA-B27+ juvenile ankylosing spondylitis.  He
is very adherent to his weekly SCIG infusions.

 

Our Rheumatologists tell me they would start anti-TNF+/- methotrexate if
he did not have XLA.

 

At how much greater risk for infection is he from this suggested
treatment versus a patient without a primary immune deficiency?  

 

Thank you for your help.

 

Joe Church

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