[CIS-PAGID] Ivasive pneumococcal disease.

[Nacho Gonzalez]

Dear Joe,

has this patient detectable levels of *properdin *(either by radial
immunodiffusion or Western blot) ?

Regards

Luis Ignacio Gonzalez-Granado
Immunodeficiencies Unit
Hospital 12 octubre. Madrid. Spain.

2011/3/16 Church, Joseph <JChurch at chla.usc.edu>


>  Colleagues:

>

>

>

> I have evaluated a 4yo boy who had pneumococcal pneumonia + empyema at

> 2.5yo.

>

>

>

> His fraternal twin died at 6mo from pneumococcal meningitis.

>

>

>

> Normal labs have included:

>

> -          CBCs

>

> -          IgG, A, M, E

>

> -          Tetanus, Hib, pneumococcal vaccine responses (including

> persistently +19/23 serotypes following Pneumovax)

>

> -          CH50

>

> -          AH50

>

> -          T, B numbers

>

> -          Mitogen and antigen LPAs

>

> -          HIV PCR

>

> -          Mannose binding lectin

>

> -          TLR function (measured at IBT Labs).

>

>

>

> What am I missing?

>

>

>

> Joe Church

>

> Clinical Immunology and Allergy

>

> Children’s Hospital Los Angeles

>

>

>

>

>

>

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