[CIS-PAGID] CVID + LIP

[Terri Tarrant]

Moving forward prospectively or historical case compilation? We're game either way.
Terri Tarrant

Sent from my iPhone


On Jul 22, 2011, at 2:15 PM, "Nelson, Robert P Jr" <ronelson at iupui.edu> wrote:


> What about considering a mutlicenter clinical trial so we could contibute our patients to an organized effort?  Bob

> ________________________________________

> From: pagid-bounces at list.clinimmsoc.org [pagid-bounces at list.clinimmsoc.org] on behalf of Fleisher, Thomas (NIH/CC/DLM) [E] [TFleishe at cc.nih.gov]

> Sent: Friday, July 22, 2011 10:32 AM

> To: Routes, John; pagid at list.clinimmsoc.org

> Subject: Re: [CIS-PAGID] CVID + LIP

> 

> Sorry for copying all on a simple question to Jack.

> 

> Thomas A. Fleisher, M.D.

> Chief, Department of Laboratory Medicine

> NIH Clinical Center

> 301 496-5668 (T)

> 301 402-1612 (F)

> 

> -----Original Message-----

> From: Routes, John [mailto:jroutes at mcw.edu]

> Sent: Friday, July 22, 2011 8:32 AM

> To: pagid at list.clinimmsoc.org

> Subject: Re: [CIS-PAGID] CVID + LIP

> 

> We have treated over ten patients with combination chemotherapy consisting of rituxin and azathioprine with outstanding results no infections and in many cased complete or near complete clearing.

> 

> Sent from my Verizon Wireless BlackBerry

> 

> ________________________________

> From: Terri Tarrant <tarra002 at gmail.com>

> Sender: "pagid-bounces at list.clinimmsoc.org" <pagid-bounces at list.clinimmsoc.org>

> Date: Fri, 22 Jul 2011 06:16:47 -0500

> To: pagid at list.clinimmsoc.org<pagid at list.clinimmsoc.org>

> ReplyTo: "pagid at list.clinimmsoc.org" <pagid at list.clinimmsoc.org>

> Subject: Re: [CIS-PAGID] CVID + LIP

> 

> Yes, we have 3 cases that responded well (2 with CVID and 1 idiopathic LIP).  We used the Eisenberg protocol of 1 g IV day 0 and day 14 with 100 mg IV solumedrol pre-med.  We did not use in combination with other drugs.  We did not see an increase in infections.  All patients needed redosing at 9-12 month intervals.

> 

> Terri Tarrant

> 

> On Thu, Jul 21, 2011 at 10:07 PM, Church, Joseph <JChurch at chla.usc.edu<mailto:JChurch at chla.usc.edu>> wrote:

> Colleagues:

> 

> A 60yo female with long term CVID has had lymphoid interstitial pneumonitis that was biopsy documented in 2005.

> 

> She had developed worsening of symptoms over the past 6 months.

> 

> She is trying to avoid increasing her prednisone, currently at 10mg/d, because of coronary artery disease and hypertension; she could not tolerate CellCept.

> 

> Has anyone tried Rituximab in this setting?

> 

> Joe Church, MD

> Children's Hospital Los Angeles

> 

> 

> 

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> --

> Terri Tarrant, MD

> Assistant Professor of Medicine

> Thurston Arthritis Research Center

> Lineberger Cancer Center Member

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