[CIS-PAGID] Quick & Dirty Neoantigen?

[Church, Joseph]

There are two problems with Menactra (conjugate) and Menomune
(uncongugated):

*	There may be some antibody in IVIG, at least with commercial lab
testing.
*	I was not impressed with the consistency of responses when I
used Menomune a few times.

 

Joe Church

Children's Hospital Los Angeles

 

________________________________

From: pagid-bounces at list.clinimmsoc.org
[mailto:pagid-bounces at list.clinimmsoc.org] On Behalf Of Brian P Vickery
Sent: Wednesday, August 10, 2011 1:06 PM
To: pagid at list.clinimmsoc.org
Subject: [CIS-PAGID] Quick & Dirty Neoantigen?

 


I follow a medically complex young man with vasculitis and
hypogammaglobulinemia and for various reasons, completing the
bacteriophage procedure is probably not feasible. Does anyone have
experience using another neoantigen in patients on IVIG, ideally one
that could be done in 4-6 wks? I had heard of folks using Menactra but
can't find any literature on it (nor in a cursory search, a place to
titer the antibody). Thought I'd throw it out to the group. 

Thanks for any thoughts- 
BPV 
___________________
Brian Vickery, MD
Division of Pediatric Allergy & Immunology
Duke University Medical Center
DUMC Box 2644, Durham NC 27710
919.681.2949

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