[CIS-PAGID] Good's syndrome

[Seppänen Mikko]

I have 3 in follow up, none of them has T-lymphopenias nor reduced mitogen responses (thus a subgroup, not representative of the whole diseases), and their IgG troughs are kept above 10 g/l (11-13), and none of them needs any prophylaxis. One had to go through FESS first, but after that has been doing fine.

However, one of them has severe oral mucosal lichen, causing scarring and a lot of discomfort and I + dentists have been completely helpless with that...

mikko

__________________________________________________
Mikko Seppänen, MD, PhD
Specialist in Internal Medicine and Infectious Diseases
Senior Consultant, Physician in charge (PIDD)
EM(E)A Expert, PIDDs and Intravenous Immunoglobulin Therapy

Immunodeficiency Unit
Division of Infectious Diseases
Department of Medicine
Helsinki University Central Hospital
Hospital District of Helsinki and Uusimaa
Aurora Hospital, Ward 4-2 and Outpatient Clinic
P.O.Box 348
FI-00029 HUS, Helsinki
FINLAND
phone +358 9 47175923, fax +358 9 47175945
_________________________________________

Lähettäjä: pagid-bounces at list.clinimmsoc.org [mailto:pagid-bounces at list.clinimmsoc.org] Puolesta Terri Tarrant
Lähetetty: 8. maaliskuuta 2012 13:59
Vastaanottaja: pagid at list.clinimmsoc.org
Aihe: [CIS-PAGID] Good's syndrome

I have a patient with newly diagnosed Good's syndrome with resected thymoma, severe hypogammaglobulinemia, absent CD19+ B cells, and recurrent sinopulmonary infections over the last 5-7 years.  There has been no documentation of severe viral, fungal, or opportunistic infections, and I have just started the patient on IgG replacement.  I wanted to query the group if you use prophylaxis in these patients, and if so, with what.

Many thanks for your thoughts,
Terri

--
Terri Tarrant, MD
Assistant Professor of Medicine
Thurston Arthritis Research Center
Lineberger Cancer Center Member
CB # 7280, 3300 Manning Dr.
Chapel Hill, NC 27599
(919) 843-4727
http://tarc.med.unc.edu/tarrant_welcome.php

-------------- next part --------------
An HTML attachment was scrubbed...
URL: <http://seven.pairlist.net/mailman/private/pagid/attachments/20120308/7817ee22/attachment.htm>