[CIS PIDD] MBL deficiency

[Richard Wasserman]

I am seeing a 43 year old female physician with a lifelong history of
recurrent sinusitis, two episodes of pneumonia in the past 10 years that
required ICU care (one of which sounds like septic shock), significant
post-op MRSA infection after sinus surgery and a large cellulitis after
stingray envenomation. Immunoglobulins are normal (IgG >1000), pneumococcal
antibody titers (14 serotypes) are strongly positive (12/14 >1ug/ml, 8/14

>5ug/ml). Mannose binding lectin was not detectable.


I know that Dr. Kirkpatrick reported a family treated successfully with
IGIV. Are there other suggestions for treatment? Antibiotic prophylaxis?
Richard Wasserman
Dallas

-- 
Richard L. Wasserman, MD, PhD
DallasAllergyImmunology
7777 Forest Lane, Suite B-332
Dallas, Texas 75230
Office (972) 566-7788
Fax (972) 566-8837
Cell (214) 697-7211
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