[CIS PIDD] [cis-pidd] Multifocal neonatal Staph

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Hi Brian,
 I would also consider STAT 3 mtations in diff.

Elif Dokmeci

On Nov 30, 2012, at 7:51 AM, "Vickery, Brian Patrick" <bvickery at email.unc.edu> wrote:


> Dear colleagues: 

> 

> What else besides physiologic immaturity should I be considering in a well-appearing, nontoxic, and non-syndromic 20 day old full-term male infant from a nonconsanguinous Caucasian family who has (presumably hematogenously spread) Staph aureus bone, joint, lung, and brain abscesses - with PMNs in the pus; normal oxidative burst; normal lymphocyte enumeration; and normal IgM & A? There are no vegetations on the TEE. Complements pending. 

> 

> This kid had a perfectly normal gestation and delivery and was feeding well when he presented to the pediatrician not moving his left arm, appearing clinically very much like an Erb's palsy. The MRI looking for a brachial plexus injury demonstrated a huge effusion with periosteal reaction in that shoulder, which ended up being a Staph abscess. 

> 

> I welcome your thoughts. 

> 

> Thanks-

> BPV

> 

> Brian P. Vickery, MD

> Assistant Professor Of Pediatrics

> University of North Carolina School of Medicine

> Campus Box #7231 | Chapel Hill, NC 27599

> 919.962.5136 | bvickery at email.unc.edu

> 

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