[CIS PIDD] [cis-pidd] CVID + "Lupus"

[Sullivan, Kathleen]

I'm a big CellCept fan for lupus but of the three drugs, MTX is the one with the least immune suppression so I might start there.  It does not have a wealth of evidence to support its use specifically for lupus but many rheumatologists will try it.

Kate
On Dec 6, 2012, at 9:47 PM, Church, Joseph wrote:


> Colleagues:

> 

> I follow a 40yo woman with fairly typical CVID.  Her rheumatologist diagnosed 'lupus' or 'non-specific connective tissue disease.'

>  

> Her chronic joint symptoms, primarily arthralgias, responded dramatically to 30 mg of prednisone per day.  As she tapered the steroid all symptoms returned.

>  

> Her rheumatologist indicated he is considering starting her on Benlysta, methotrexate or Cellcept. 

>  

> Is there a "lesser evil" among these drugs for a patient with CVID?

>  

> JC

> 

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Kate Sullivan, MD PhD
Professor of Pediatrics
ARC 1216 Immunology CHOP
3615 Civic Center Blvd.
Philadelphia, PA 19104
(p) 215-590-1697
(f) 267-426-0363



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