[CIS PIDD] [cis-pidd] Yellow fever vaccine

[Kobrynski, Lisa]

I spoke with my local CDC infectious disease expert.  Yellow fever vaccination is not contraindicated for someone living with an immunocompromised person (e.g. household contact), therefore there should be no risk for a CVID patient coming in contact with someone who has received the yellow fever vaccine.

Unless absolutely indicated, I don't advocate giving yellow fever vaccine to anyone due to the risk of develping complications such as Guillaume Barre following vaccination.

Hope that helps.

Lisa



Lisa Kobrynski, MD, MPH
Associate Professor of Pediatrics
Marcus Professor of Immunology
Section, Allergy/Immunology
________________________________
From: Michael Blaese [mblaese at comcast.net]
Sent: Monday, December 10, 2012 9:24 PM
To: CIS-PIDD
Subject: [cis-pidd] Yellow fever vaccine

Dear colleagues,

IDF has received the following inquiry from a caregiver for a patient with CVID.

 QUESTION: My daughter may be exposed to a person who is taking typhoid fever pills and a yellow fever shot for a trip to India. Is it necessary to avoid the person or how much contact with the person can be made safely?

Is there a risk of horizontal spread of yellow fever vaccine from a recently immunized individual to a patient with CVID?  The CDC recommendation is to not allow recently vaccinated individuals to donate blood for 2 weeks, but I have not been able to find information on the potential risk of horizontal spread from ordinary contact.  Does anyone have experience with the direct immunization of a CVID patient with the yellow fever vaccine causing significant problems for the patient?

Any information you can provide would be greatly appreciated.   Maybe someone from a yellow fever endemic area might have direct experience with this question that just does not come up very often in the northern U.S.

Thanks

R Michael Blaese,  MD
Immune Deficiency Foundation

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