[CIS PIDD] [cis-pidd] Nausea with IVIG infusions

Pere Soler Palacin psoler at vhebron.net
Sat Jan 26 07:04:30 EST 2013




Dear all, I absolutely agree with Robert. We have some similar cases both with IVIG and with other kind of treatment. Premedication  (a couple of hours before) with lorazepam (1mg) and psicological support may be helpful.



Pere.



Pere Soler Palacín, MD, PhD. Pediatric Infectious Diseases and Immunodeficiencies Unit. Hospital Universitari Vall d'Hebron.     Assistant Professor. Universitat Autònoma de Barcelona.                                                      
Passeig de la Vall d'Hebron 119-129.
08035 Barcelona. Spain.
Tel: 0034934893140. Fax: 0034934893039.
E-mail: psoler at vhebron.net ; 34660psp at comb.cat . Web: www.upiip.com .
 

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Pere Soler Palacín, MD, PhD. Pediatric Infectious Diseases and Immunodeficiencies Unit. Hospital Universitari Vall d'Hebron.     Assistant Professor. Universitat Autònoma de Barcelona.                                                      
Passeig de la Vall d'Hebron 119-129.
08035 Barcelona. Spain.
Tel: 0034934893140. Fax: 0034934893039.
E-mail: psoler at vhebron.net ; 34660psp at comb.cat . Web: www.upiip.com .
 

No imprimir aquest correu ajudarà a preservar el medi ambient.
Si vostè no és el destinatari del missatge, o l'ha rebut per error, si us plau notifiqui-ho al remitent i destrueixi el missatge amb tot el seu contingut. Està prohibida la distribució no autoritzada del contingut d'aquest missatge.

No imprimir este correo ayudará a preservar el medio ambiente.
Si usted no es el destinatario del mensaje, o lo ha recibido por error, notifíquelo por favor al remitente y destruya el mensaje con todo su contenido. Está prohibida la distribución no autorizada del contenido de este mensaje.

----- Mensaje original -----
De: "Robert Sokolic (NIH/NHGRI) [E]" <sokolicr at mail.nih.gov>
Para: "CIS-PIDD" <cis-pidd at lists.clinimmsoc.org>
Enviados: Sábado, 26 de Enero 2013 12:55:05
Asunto: RE:[cis-pidd] Nausea with IVIG infusions

If she is having nausea immediately as the infusion starts, it may be similar to anticipatory nausea with chemotherapy. Ativan works well for this.
RS
________________________________________
From: Church, Joseph [JChurch at chla.usc.edu]
Sent: Friday, January 25, 2013 7:26 PM
To: CIS-PIDD
Subject: [cis-pidd] Nausea with IVIG infusions

Colleagues:

I follow a young adult woman with CVID who has had multiple problems, originally severe headaches, with Ig infusions.  We have tried SCIG (hated), IVIG q4 and q2weeks, premedications with iv diphenhydramine and motrin.

Most recently she has done better with regards to headache on a q week schedule with pre-Ig hydration, motrin and iv diphenhydramine, and Maxault prn

Now her complaint is nausea that she states starts soon after the IVIG begins infusing and worsens over the next 12-24 hours despite use of Phenergan (not my Rx) and Zofran.

Any thoughts?

Thanks in advance.

Joe Church
Children's Hospital Los Angeles



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