[CIS PIDD] [cis-pidd] Subcutaneous Plaques following immunoglobbulin infusions

[Heimall, Jennifer]

I have an 18y/o patient with specific antibody deficiency who was treated with subcutaneous immunoglobulin replacement.  After about 10 months, she developed painful nodules on the left flank.  We encouraged rotation of infusion sites and tried a change of product.

Despite these changes and having been off of subcutaneous immunoglobulin for the last 2 months, she now has large (11cmx6cm), tender, firm plaques with overlying hyperpigmentation present on both sides of her lower abdomen.

Has anyone else encountered this with patients on subcutaneous immunoglobulin?







Jennifer Heimall, MD
The Children's Hospital of Philadelphia
Allergy/Immunology
3550 Market Street
3rd Floor
Philadelphia, PA 19104
phone: (267)426-9231

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