[CIS PIDD] [cis-pidd] 12 yo with oral candidiasis

[Amos Etzioni]

Hi Richard
The next step is to look at the number of TH17 cells and then to look at the level of IL-17A and more cytokines
Amos

Amos Etzioni MD
Professor of Pediatrics and Immunology
Director - Meyer Children's Hospital
Bat- Galim, Haifa, Israel 31096
Tel- 972-4-854 2936
Fax- 972-4-854 1870
Email - etzioni at rambam.health.gov.il



From: Richard Wasserman [mailto:drrichwasserman at gmail.com]
Sent: Tuesday, July 23, 2013 2:58 PM
To: CIS-PIDD
Subject: [cis-pidd] 12 yo with oral candidiasis

I am seeing a 12 yo who presented with oral candidiasis for the first time two months ago. He was treated with nystatin and cleared. One month later the candida returned.

He had been well with no significant infection history, no exposure to oral or inhaled corticosteroids and one course of antibiotics a few months before presentation. There is no significant past medical or family history. When I saw him, the physical examination was normal.

CBC, IgA, IgG, IgM, CD3, 4,8, 19 and 16/56 were all normal, ANA was negative.

The proliferative response to PHA, ConA and PWM and to tetanus were all vigorous. The response to candida was <50% of the lower limit of normal.

What is the best next step?

Thank you,
Richard Wasserman
Dallas

--
Richard L. Wasserman, MD, PhD
DallasAllergyImmunology
7777 Forest Lane, Suite B-332
Dallas, Texas 75230
Office (972) 566-7788
Fax (972) 566-8837
Cell (214) 697-7211

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