[CIS PIDD] [cis-pidd] 12 yo with oral candidiasis

[Richard Wasserman]

Thank you for your suggestions. Does anybody have a thought about why a
STAT1/TH17 related problem would present for the first time at age 12?
Richard


On Tue, Jul 23, 2013 at 9:50 AM, Church, Joseph <JChurch at chla.usc.edu>wrote:


>  Richard:

>

> Consider contacting Jean-Laurent Casanova at Rockefeller for *STAT1* and

> perhaps other genes.****

>

> ** **

>

> Joe Church****

>

> ** **

>

> *From:* Richard Wasserman [mailto:drrichwasserman at gmail.com]

> *Sent:* Tuesday, July 23, 2013 4:58 AM

> *To:* CIS-PIDD

> *Subject:* [cis-pidd] 12 yo with oral candidiasis****

>

> ** **

>

> I am seeing a 12 yo who presented with oral candidiasis for the first time

> two months ago. He was treated with nystatin and cleared. One month later

> the candida returned.****

>

> ** **

>

> He had been well with no significant infection history, no exposure to

> oral or inhaled corticosteroids and one course of antibiotics a few months

> before presentation. There is no significant past medical or family

> history. When I saw him, the physical examination was normal. ****

>

> ** **

>

> CBC, IgA, IgG, IgM, CD3, 4,8, 19 and 16/56 were all normal, ANA was

> negative.****

>

> ** **

>

> The proliferative response to PHA, ConA and PWM and to tetanus were all

> vigorous. The response to candida was <50% of the lower limit of normal.**

> **

>

> ** **

>

> What is the best next step?****

>

> ** **

>

> Thank you,****

>

> Richard Wasserman****

>

> Dallas

> ****

>

> ** **

>

> --

> Richard L. Wasserman, MD, PhD

> DallasAllergyImmunology

> 7777 Forest Lane, Suite B-332

> Dallas, Texas 75230

> Office (972) 566-7788

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> Cell (214) 697-7211 ****

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-- 
Richard L. Wasserman, MD, PhD
DallasAllergyImmunology
7777 Forest Lane, Suite B-332
Dallas, Texas 75230
Office (972) 566-7788
Fax (972) 566-8837
Cell (214) 697-7211

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