[CIS PIDD] [cis-pidd] IVIG dosing based on ideal body weight

[Kirkpatrick, Charles]

Chris:

This has become an issue in Colorado.  The insurance companies are pushing ideal weight.  The infusion centers are pushing for actual weight unless the patient does not have good insurance coverage.  Then ideal weight seems to be OK.

I am waiting to see if either schedule has any impact on clinical responses.  Too soon to tell.  My usual dose for adults is 400 mg/kg actual weight.

Chuck Kirkpatrick

From: Christine M. Seroogy, MD [mailto:cmseroogy at pediatrics.wisc.edu]
Sent: Tuesday, July 30, 2013 4:25 PM
To: CIS-PIDD
Subject: [cis-pidd] IVIG dosing based on ideal body weight

Dear colleagues,

I am interested in hearing how many of you dose IVIG for adults based on ideal body weight (IBW)?  Given that gamma globulin is a precious resource and a significant portion of most pharmacy budgets, our pharmacists have approached me about this strategy.  I couldn't find substantive medical evidence using this dosing regimen for immune deficient patients. I imagine the approach is individualized using clinical correlates, but am interested in hearing the group's thoughts on how many have initiated therapy based on IBW or transitioned to IBW for their patients. And if so, was this effective?

Thank you

Chris


Christine M. Seroogy MD,  FAAAAI
Associate Professor
University of Wisconsin
Department of Pediatrics
Division of Allergy, Immunology & Rheumatology
1111 Highland Avenue
4139 WIMR
Madison, WI  53705-2275
phone: 608-263-2652
fax: 608-265-9721





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