[CIS PIDD] [cis-pidd] Nodular lymphoid hyperplasia and rituximab

[Nacho Gonzalez]

Dear Kate,

I treated one CVID patient once in 2010 with RTX 375/m2 x 4 weeks (for
AIHA) and in 2012 (AIHA relapsed). She had severe NLH in 2012 (portal
hypertension with esophageal varices). The patient has stable liver disease
since then, but RTX did not prevent NLH 2 years after the first exposure.
Has anyone tried bortezomib for NLH?

Best regards,
Luis Ignacio Gonzalez-Granado
Immunodeficiencies
Hematology & Oncology
Hospital 12 octubre
Madrid. Spain


2014-04-04 14:03 GMT+02:00 Sullivan, Kathleen <sullivak at mail.med.upenn.edu>:


> Hi everyone!

>

> I have an adult CVID patient with VERY severe NLH.  I treated him with

> rituximab but the insurance company is now refusing to pay.  Does anyone

> have ANY references for the use of rituximab in this condition?  I can't

> find any in PubMed and the insurance company will not re-review unless I

> can give them some data.

>

> Thanks!

>

> Kate

>  Sullivan, Kathleen, MD PhD

> Professor of Pediatrics

> Wallace Chair of Pediatrics

> Division of Allergy Immunology

> The Children's Hospital of Philadelphia

> ARC 1216

> 3615 Civic Center Blvd

> Philadelphia, PA 19104

> sullivak at mail.med.upenn.edu

>

>

>

>

>

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