[CIS PIDD] [cis-pidd] 14yo with recurrent Staph aureus sepsis

[Heimall, Jennifer]

Any other history of eczema, fungal infection or warts?  Any elevation in ige or eosinophilia? I am thinking of perhaps a DOCk8- some were not too sick until their teens.
Jen

Sent from my iPhone

On Jun 2, 2014, at 7:56 PM, "Church, Joseph" <JChurch at chla.usc.edu<mailto:JChurch at chla.usc.edu>> wrote:

Colleagues:

I was asked to evaluate a previously very healthy 14yo boy who experienced the following:

·         2012 Cellulitis (likely Staph) after an insect bite

·         2013 Staph aureus, methicillin sensitive, septic shock after minor skin trauma and possible local infection

·         2014 Staph aureus, methicillin sensitive, sepsis.

He has a past history of a 4mm VSD, but echocardiography on two occasions failed to reveal a focus of infection.

Neutrophil counts were repeatedly normal.

Physical exam is normal except for a III/VI ejection murmur.

I have never read that CGD or LAD presents like this.  I plan to suggest a closer look at his heart valves.  Any other suggestions?

Joe Church
Children’s Hospital Los Angeles

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