[CIS PIDD] [cis-pidd] Severe aphthous ulcers in an adolescent with CVID

Juan Carlos Aldave Becerra jucapul_84 at hotmail.com
Thu Jun 5 08:36:16 EDT 2014


Dear Jane,
I am not sure that it would work in Your patient, but many of my patients with aphtous ulcers of different causes have improved with zinc supplements, which is a very safe therapy.
Best regards,
Juan Carlos Aldave
Allergy and Clinical Immunology
Lima, Peru

Enviado desde mi iPhone

> El 05/06/2014, a las 01:22, "Jane Peake" <j.peake at uq.edu.au> escribió:
> 
> Hi all
> I have a young girl with CVID who has been plagued with severe disabling aphthous ulcers for many years. Since starting on IVIg her infectious problems have largely resolved and her ulcers are better but they are still problematic. She gets them on her tongue, buccal mucosa and roof of the mouth and when she has them she finds eating and speech very difficult. Episodes are intermittent but she rarely goes more than a couple of weeks without a severe episode. She has had a couple of episodes of labial lesions but since starting doxycycline (on the advice of the gynaecologists) she has only had one episode when they had run out of the doxycycline. We have tried a variety of topical treatments – local anaesthetics and steroids. She responds well to oral steroids but these cannot be used regularly. Does anybody have any other ideas in this setting?
> Thanks for any suggestions
> Cheers Jane
>  
> Dr Jane Peake
> Paediatric Immunologist and Allergist
> Senior Lecturer
> University of Queensland
> level 3 Foundation Building
> Royal Children's Hospital
> Herston Rd, Herston QLD 4029
>  
>  
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