[CIS PIDD] [cis-pidd] Protein losing enteropathy

[Boyce, Thomas G., M.D.]

Santhosh,

It is difficult to replete even if you wanted to as they tend to lose the IgG in the stools almost as fast as you can give it.

Tom Boyce
Peds ID
Mayo Clinic

On Jul 23, 2014, at 5:28 PM, "Santhosh Kumar/FS/VCU" <skumar at vcu.edu<mailto:skumar at vcu.edu>> wrote:

Hello,
I would appreciate any input regarding this case. I tried to search the literature but  there is not much on this topic.
I am seeing a 4 y/o child in consultation with GI who has protein losing enteropathy which they are trying to figure out the cause. He has had an endoscopy and colonoscopy which are normal. His immunoglobulins are  trending down and most recent one is IgG 164, IgM 24, IgA 73. His lymphocyte enumeration is normal. His vaccine titers were low to start with but have responded well to vaccination challenge. He has no hx of recurrent infections. I was wondering if there is any reason to treat him with IVIG. The IgG level makes me little nervous but given his vaccine titers are protective i am willing to observe.

Thank you,

Santhosh Kumar, MD
Assistant Professor,
Training Program Director
Allergy & Immunology
Medical College of Virginia
Ph:804-628-1605
Fax-804-828-1751

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