[CIS PIDD] [cis-pidd] therapeutic advise for severe Respiratory papillomatosis (RRP)

Notarangelo, Luigi Luigi.Notarangelo at childrens.harvard.edu
Fri Sep 26 14:23:15 EDT 2014


Dear Elie,

I agree with Dr. Aldave that systemic administration would be preferable for IFN-a.

Best regards,


Luigi D. Notarangelo, MD
Professor of Pediatrics and Pathology
Harvard Medical School
Jeffrey Modell Chair of Pediatric Immunology Research
Division of Immunology, Children's Hospital Boston
Karp Research Building, Room 10217
1, Blackfan Circle
Boston, MA 02115

tel: (617)-919-2277
FAX: (617)-730-0709



From: Elie Haddad <elie.haddad at umontreal.ca<mailto:elie.haddad at umontreal.ca>>
Reply-To: CIS-PIDD <cis-pidd at lists.clinimmsoc.org<mailto:cis-pidd at lists.clinimmsoc.org>>
Date: Friday, September 26, 2014 at 2:05 PM
To: CIS-PIDD <cis-pidd at lists.clinimmsoc.org<mailto:cis-pidd at lists.clinimmsoc.org>>
Subject: [cis-pidd] therapeutic advise for severe Respiratory papillomatosis (RRP)

Dear colleagues,
We have a 13 yo patient with severe respiratory papillomatosis.
Her lesions are progressing in the larynx and although a new surgery is scheduled, the ENT specialist is very worried and asked us for help.
I know that some years ago, someone posted the feasibility of IFNa in aerosol for these patients, but I cannot find the post.
Does anyone know how to do this (doses, frequency, solution) ?
Do you think it is a good idea ?
Do you think we should give systemic IFNa also (or only) ?
Any anti-viral drug that could help ?
Thanks
Elie


Elie Haddad, MD, PhD,
Professor of Pediatrics, University of Montreal,
Head, Pediatric Immunology and Rheumatology Division,
CHU Sainte-Justine, 3175 Cote Sainte-Catherine
Montreal, QC, H3T 1C5, Canada
Ph: 1 514 345 4713
fax: 1 514 345 4897
e-mail: elie.haddad at umontreal.ca<mailto:elie.haddad at umontreal.ca>






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