[CIS PIDD] [cis-pidd] CTLA4 haploinsufficiency treatment

[Shahlaee, Amir]

Could the leukopenia be drug induced? Cellcept can do that.
Has a marrow biopsy/aspirate been done?

Amir Shahlaee
GRU Allergy-Immunology
________________________________
From: Abbott, Jordan [AbbottJ at NJHealth.org]
Sent: Friday, November 14, 2014 3:07 PM
To: CIS-PIDD
Subject: [cis-pidd] CTLA4 haploinsufficiency treatment


All,
We are following a 17 year old with a CTLA-4 mutation who presented with severe hemolytic anemia, GLILD, leukopenia who responded to Cellcept. He has now developed severe leukopenia.
Any thoughts on therapies short of BMT. Heard that patients may not have responded well to abatacept.
Thanks



Erwin W. Gelfand, M.D.
Chairman, Department of Pediatrics
National Jewish Health
1400 Jackson Street
Denver, CO 80206
Ph: 303-398-1196
Fax: 303-270-2105
E-mail: gelfande at njhealth.org<mailto:gelfande at njhealth.org>


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