[CIS PIDD] PEG-ADA in pregnancy

[Kobrynski, Lisa]

Does anyone have experience treating a patient with ADA-SCID who is receiving PEG-ADA?

This is a patient who has not received gene therapy or transplant and is remarkably well only treated with PEG-ADA replacement.



Specifically - would you change the dosing to compensate for increased blood volume?

Would you monitor for any specific problems with the pregnancy (mom or baby)?



This is a rather novel experience for most of us so hopefully someone out there has had experience with this.

Thanks

Lisa







Lisa Kobrynski, MD, MPH
Associate Professor of Pediatrics
Marcus Professor of Immunology
Section, Allergy/Immunology

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