[CIS PIDD] [cis-pidd] HPV Vaccine in CVID or SAD

[Ravishankar.Sargur at sth.nhs.uk]

Dear Joe,

We have done this in about 3 patients who had warts on their fingers.  Not aware of the data about HPV antibodies.
Reasoning was it would help induce T cell response and they are at a higher risk as they have shown an increased susceptibility to HPV.

There is also some evidence in the literature to show potential epitope spreading and protection against other HPV types not in the vaccine.
We used the 4 valent vaccine.

Ravi

Dr Ravishankar Sargur
MD, FRCPath, FRCP
Consultant Clinical Immunologist & Clinical Lead
Protein Reference Unit, Immunology, NGH
Sheffield Teaching Hospitals Foundation NHS Trust.

Training Programme Director
Immunology
East Midlands Deanery and Yorkshire & Humber Deanery
Email : Ravishankar.sargur at sth.nhs.uk<mailto:Ravishankar.sargur at sth.nhs.uk>
Phone : 0114 2715704
Hayley Rowan ( Secrretary) : 0114 2269020
Fax : 0114 2269244







From: Church, Joseph [mailto:JChurch at chla.usc.edu]
Sent: 27 March 2015 00:39
To: CIS-PIDD
Subject: [cis-pidd] HPV Vaccine in CVID or SAD

Colleagues:

This question arose twice today in clinic:  should youth with CVID or Specific Antibody Deficiency, and who are receiving Ig replacement therapy, be given HPV vaccine?

Does anyone know if current Ig products contain antibodies to the HPV types in the available vaccines?

Joe Church
Children's Hospital Los Angeles



---------------------------------------------------------------------
CONFIDENTIALITY NOTICE: This e-mail message, including any attachments,
is for the sole use of the intended recipient(s) and may contain confidential
or legally privileged information. Any unauthorized review, use, disclosure
or distribution is prohibited. If you are not the intended recipient, please
contact the sender by reply e-mail and destroy all copies of this original message.

---------------------------------------------------------------------

---

You are currently subscribed to cis-pidd as: ravishankar.sargur at sth.nhs.uk<mailto:ravishankar.sargur at sth.nhs.uk>.

To unsubscribe click here: http://cts.dundee.net/u?id=96396863.eec3ce444ba28ca140c47ceb1a2cb6f3&n=T&l=cis-pidd&o=2700301

(It may be necessary to cut and paste the above URL if the line is broken)

or send a blank email to leave-2700301-96396863.eec3ce444ba28ca140c47ceb1a2cb6f3 at lyris.dundee.net<mailto:leave-2700301-96396863.eec3ce444ba28ca140c47ceb1a2cb6f3 at lyris.dundee.net>

---
You are currently subscribed to cis-pidd as: pagid at list.clinimmsoc.org.
To unsubscribe click here: http://cts.dundee.net/u?id=96396833.5a9591ccd1e327fe6bc4d1543298c482&n=T&l=cis-pidd&o=2701339
or send a blank email to leave-2701339-96396833.5a9591ccd1e327fe6bc4d1543298c482 at lyris.dundee.net
-------------- next part --------------
An HTML attachment was scrubbed...
URL: <https://pairlist7.pair.net/pipermail/pagid/attachments/20150327/54835456/attachment-0001.html>