[CIS PIDD] [cis-pidd] HHV6 meningoencephalitis

[Mel.Berger at cslbehring.com]

Can you assess IFN production by ELISpot or intracellular flw ?
________________________________
From: Maite de la Morena [Maite.delaMorena at UTSouthwestern.edu]
Sent: Friday, June 19, 2015 5:54 PM
To: CIS-PIDD
Subject: [cis-pidd] HHV6 meningoencephalitis

Dear all
I have seen a 4 yof who developed HHV6 meningoencephalitis at age 3 and now has seizures, now severe developmental delay.
Had been achieving milestones appropriately until then

Negative serologies for CMV, EBV, HSV but + IgG for HHV6 (Negative IgM),
serum Igs and specific response to vaccines normal, Normal flow and normal mitogens and antigens .
Normal perforin, NK function and CTLs and TLR signaling ( ARUP )

She has not received MMR or varicella. I am hesitant to give these.
Would appreciate your comments
Thank you
Maite

Maite de la Morena, MD
Professor of Pediatrics  and Internal Medicine
Division of Allergy and Immunology
University of Texas Southwestern Medical Center in Dallas
5323 Harry HInes Blvd
Dallas, Texas 75390-9063
Phone 214 456-5161
Fax: 214 456-8317
Email: maite.delamorena at utsouthwestern.edu


________________________________

UT Southwestern


Medical Center



The future of medicine, today.


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