[CIS PIDD] [MARKETING][cis-pidd] chronic cutaneous HSV I

[CIS-PIDD]

I would still try valaciclovir 1g x3/d, long term, and give advice on avoiding direct sunlight.

Some of these are tough to control. Of recent advances in pathogenesis, I found this enlightening:

Identification of novel gene signatures in patients with atopic dermatitis complicated by eczema herpeticum.
Bin L, et al. J Allergy Clin Immunol. 2014

Hope she tolerates an increased dose?

Mikko

Oyl Mikko Seppänen
Harvinaissairauksien yksikkö (HAKE)

Head, Rare Disease Center,
Helsinki University Hospital (HUH)
FINLAND

phone +358 947180201
GSM +358 50 4279606
fax +358 9 47174703

CIS-PIDD <cis-pidd at lists.clinimmsoc.org<mailto:cis-pidd at lists.clinimmsoc.org>> kirjoitti 25.1.2016 kello 17.17:

I have cared for a 27yo female with a lifelong history of difficult topic diatheses; eczema, asthma, allergic rhinitis, chronic urticaria and food allergy. She has never had any significant infection problems except for chronic cutaneous HSV I that is usually but not always suppressed with valacyclovir 1g twice a day. She is very medication dependent and if she misses a dose has an exacerbation. Her major problem is on her face. Her eczema is currently under good control with minimal use of low potency topical steroids or caclineurin inhibitors. I'd appreciate any suggestions for management.
Richard Wasserman

--
Richard L. Wasserman, MD, PhD
Allergy Partners of North Texas
7777 Forest Lane, Suite B-332
Dallas, Texas 75230
Office (972) 566-7788
Fax (972) 566-8837
Cell (214) 697-7211

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