[CIS PIDD] [cis-pidd] IGSC for autoimmune disorders

[CIS-PIDD]

We have the same data, although in fewer patients.
ScIg is as good as IVIG for preventing autoimmune relapses. However, ScIg is not as efficient as IVIG for inducing a remission of an autoimmune process. Few cases experience, I am not saying this in the context of a controlled trial.

Elie Haddad
CHU Sainte-justine, Montreal, Canada


On Jun 16, 2016, at 18:53, CIS-PIDD <cis-pidd at lists.clinimmsoc.org<mailto:cis-pidd at lists.clinimmsoc.org>> wrote:

We did a retrospective (5 yr) study on 60 CVID with ITP, and SCIG was as good as IVIG substitution in preventing additional bouts of ITP… still to be published…
Best, Bodo

****************************************
Univ.-Prof. Dr. med. B. Grimbacher

Scientific-Director
CCI-Center for Chronic Immunodeficiency
UNIVERSITÄTSKLINIKUM FREIBURG
Tel.: 0761 270-77731  Fax: -77744
Breisacherstraße 115, 79106 Freiburg
bodo.grimbacher at uniklinik-freiburg.de<mailto:bodo.grimbacher at uniklinik-freiburg.de>
www.uniklinik-freiburg.de/cci<http://www.uniklinik-freiburg.de/cci>

and

Consultant Immunologist
Institute of Immunity & Transplantation
Dept of Immunology
Royal Free Hospital
UNIVERSITY COLLEGE LONDON
Pond Street
London NW3 2QG
b.grimbacher at ucl.ac.uk<mailto:b.grimbacher at ucl.ac.uk>
www.centreforimmunodeficiency.com<http://www.centreforimmunodeficiency.com>

Von: CIS-PIDD <cis-pidd at lists.clinimmsoc.org<mailto:cis-pidd at lists.clinimmsoc.org>>
Antworten an: CIS-PIDD <cis-pidd at lyris.dundee.net<mailto:cis-pidd at lyris.dundee.net>>
Datum: Thursday 16 June 2016 07:48
An: CIS-PIDD <cis-pidd at lyris.dundee.net<mailto:cis-pidd at lyris.dundee.net>>
Betreff: Re: [cis-pidd] IGSC for autoimmune disorders

Joe, one preschool girl with chronic ITP and recurring bleedings who did not really respond to other measures than ivig (required almost biweekly, but family didn't want to spend a day in the hospital every two weeks) runs very well now on scig at a substitution (low) dose; I am currently trying to extend the interval to biweekly.

Univ.-Prof. Dr. Markus G. Seidel | Päd. Häm. Onk. | Med. Univ. Graz | Auenbruggerpl. 38, A-8036 Graz, Austria | Tel +4331638512621 | Fax +4331638513717 | Secr +4331638513485 | sent from my mobile phone | please excuse typos

Am 16.06.2016 um 00:50 schrieb CIS-PIDD <cis-pidd at lists.clinimmsoc.org<mailto:cis-pidd at lists.clinimmsoc.org>>:

Colleagues:

Has anyone used the subcutaneous route to administer ‘high dose’ immunoglobulin (2g/kg) to patients with autoimmune disease?

Joe Church
Children’s Hospital Los Angeles

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