[CIS PIDD] [cis-pidd] yellow fever vaccine

[CIS-PIDD]

The pt doesn't look to have any contraindication for YF vaccine...or strong indication for IgG replacement either. Not sure about the YF titers on US plasma donors as if present they should neutralize a live virus vaccine (for full info on simultaneous or sequential use of bilogicals -eg vaccines and IgG- check the ACIP/CDC recommendation guidelines)
Sergio

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On Sep 18, 2016 12:34:14 PM, CIS-PIDD <cis-pidd at lists.clinimmsoc.org> wrote:


Dear sir -

If your patient responded to pneumococcal vaccine, does not have hypogammaglobulinemia, and hasn't had issue with prior live vaccines, I would think that the yellow fever vaccine should be tolerated well and is probably advisable.

Has he received and tolerated zostavax?

Best regards,
Mike



Michael D. Keller, MD

Assistant Professor, Division of Allergy / Immunology

Center for Cancer and Immunology Research

Jeffrey Modell Diagnostic and Research Center for

Primary Immunodeficiency Disorders

Children's National Health System

111 Michigan Ave NW, M7745A

Washington, DC 20010

Clinic: 202.476.3016

Office: 202.476.5843

Fax: 202.476.2280

www.ChildrensNational.org


________________________________
From: CIS-PIDD [cis-pidd at lists.clinimmsoc.org]
Sent: Sunday, September 18, 2016 11:17 AM
To: CIS-PIDD
Subject: [cis-pidd] yellow fever vaccine


I have a patient who is a 50 year old man with S. aureus chronic rhinosinusitis with polyps.  He has been diagnosed with selective antibody deficiency, mild phenotype (responded to 20/23 serotypes).   His immunoglobulin  levels and IgG subtypes were normal, and he apparently responded to DT. I have not yet obtained the actual results yet from the DT.  CD3,4,8 were normal.  He was started on IgG replacement because he was not responsive to any other treatment.  There has been some improvement.

The patient is traveling to Ethiopia for which the live yellow fever vaccine is recommended.  The ID person who follows him is reluctant to give him the vaccination given his immunodeficiency diagnosis.  My thoughts are that since this would be considered a mild antibody deficiency, it would be advisable to give it.

Thoughts?

Thanks.

Sincerely,

Wellington S. Tichenor, M. D.
642 Park Avenue
New York, New York 10065
212 517-6611
wtichenor at sinuses.com<https://urldefense.proofpoint.com/v2/url?u=https-3A__register.concentric.com_home_apps_mail_mbox-5Fcompose.cgi-3FpTo-3Dwtichenor-40sinuses.com&d=DQMFAw&c=Zoipt4Nmcnjorr_6TBHi1A&r=mERX_I8PKb0Uil9coedoT1CtvFqkSey45L0vbcX0oKI&m=-QDXL0Bp28l2u4CZWxPOVyR5Sw2Y9-QRg2e1djGSkyA&s=ibJGGbfoMM-ob4NuY8WG43d5TrM7_sIBRRPPDmThHyo&e=>


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