[CIS PIDD] [cis-pidd] CVID/Antibody defect

[CIS-PIDD]

With respect to malignancy surveillance, the party line on most types of cancer predispositions is for the patient to follow routine cancer screening recommendations. Primary care guys can be as good for that as oncologists. There is no screening for lymphoma other than PE for lymphadenopathy and questions about B symptoms. If your BMP includes LDH, that would be a screen as well, but I would not order it otherwise as the performance characteristics of such screening are unknown. (One of my residents when I was an intern told me that LDH stands for Little Damn Help.)
-R


--
Rob Sokolic, MD
Medical Officer
Center for Biologics Evaluation and Research
Office of Tissues and Advanced Therapies
U.S. Food and Drug Administration
Tel: 240-402-5564
Robert.Sokolic at fda.hhs.gov<mailto:Robert.Sokolic at fda.hhs.gov>
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From: CIS-PIDD [mailto:cis-pidd at lists.clinimmsoc.org]
Sent: Thursday, February 23, 2017 10:31 AM
To: CIS-PIDD
Subject: [cis-pidd] CVID/Antibody defect

Good Morning Colleagues,

I wanted to inquire about regular surveillance of our patietns with CVID/Antibody defects. Besides a chest CT, PFT, BMP, LFTs, CBC, IgG, is there a consensus of other things we should be monitoring regularly? (CT Abd Pelvis, refer to Heme/Onc for malignancy surveillance) and if so how frequently?

I appreciate all the recommendations,

pam

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