[CIS PIDD] [cis-pidd] ADA2 deficiency - Infliximab dosage

[CIS-PIDD]

Thanks Stefano. 

Sent from my iPhone

> On 19 May 2017, at 07:06, CIS-PIDD <cis-pidd at lists.clinimmsoc.org> wrote:
> 
> Dear Fabian,
> 
> Marco Gattorno just reported 15 DADA2 patients with an inflammatory phenotype (stroke/PAN...). 
> 11/15 were treated with etanercept (none with infliximab), 10/11 had a complete response, 1 had a partial response.
> 
> Caorsi R, et al. Ann Rheum Dis 2017;0:1–9
> http://dx.doi.org/10.1136/annrheumdis-2016-210802
> 
> 
> 
> Stefano Volpi, MD, PhD
> IRCCS Istituto G. Gaslini, Italy
> stefanovolpi at gaslini.org
> 
> 
> 
> 
>> On 16 May 2017, at 20:15, CIS-PIDD <cis-pidd at lists.clinimmsoc.org> wrote:
>> 
>> Dear Fabian,
>> 
>> Why would you use infliximab as opposed to etanercept? 
>> 
>> Isabelle Meyts, UZ Leuven
>> 
>> 
>> 
>> 
>>> Op 16-mei-2017 om 17:00 heeft CIS-PIDD <cis-pidd at lists.clinimmsoc.org> het volgende geschreven:
>>> 
>>> Dear all,
>>>  
>>> I am planning to treat an ADA2 deficient patient with Infliximab and would like to know the dosage and the dosing intervall already used sucessfully.
>>> Is it 5mg/kg at week 0, 2, 6 and thereafter every 8 weeks?
>>>  
>>> Thank you and best regards,
>>>  
>>> Fabian
>>>  
>>>  
>>> Fabian Hauck, MD, PhD
>>>  
>>> Head Immunodeficiency Unit and Immunological Diagnostics Laboratoy
>>> Pediatrics / Pediatric Hematology and Oncology / Immunology (DGfI)
>>>  
>>> Dr. von Hauner Children’s Hospital
>>> Klinikum der Universität München 
>>> Lindwurmstr. 4, 80337 München
>>> Germany
>>>  
>>> Tel.: +49 89 4400-53931
>>> Fax: +49 89 4400-53964
>>> E-Mail: fabian.hauck at med.uni-muenchen.de
>>>  
>>>  
>>> www.klinikum.uni-muenchen.de
>>>  
>>> <image001.png>
>>>  
>>> Das Klinikum der Universität München ist eine Anstalt des öffentlichen Rechts (AöR)
>>> The Klinikum der Universität München is an Institution under Public Law
>>>  
>>>  
>>>  
>>> 
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