[PAGID] CVID fatigue

[Riedl, Marc]

I have a 58 yo previously healthy woman recently diagnosed with CVID (IgG
400, low IgA, h/o respiratory infections) who has suffered from profound
disabling persistent fatigue for the past year. Increasing her IgG dose has
had no effect, nor is the fatigue cyclical related to her infusions.  We
have looked for chronic infection or monoclonal gammopathy without any
findings.  She was formerly a successful, high-powered attorney and appears
very motivated to return to work but has "no energy".  I have a sizeable
number of CVI patients in my practice and have seen associated fatigue, but
not to this degree or intensity.

Does anyone have experience with this?  Any suggestions are appreciated.


Thanks,

Marc

Marc Riedl, M.D., M.S. 
Assistant Professor of Medicine 
Clinical Immunology and Allergy 
UCLA - David Geffen School of Medicine 
10833 Le Conte Ave, 52-175 CHS 
Los Angeles, CA  90095 
Tel 310.206.4345  Fax 310.206.8107

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