[PAGID] Hyper IgE therapy?

[Charlotte Cunningham-Rundles]

we have used WBC infusions in this scenario ( brain abscess in that 
case) and I know the NIH has as well.

  I don't   know if G(M) -CSF has been used, but we have used  GM-CSF 
in CGD with terrible GI disease which helped avoid colostomy



>We have just received an very ill 28 yo man with alleged Hyper IgE 

>ID who is septic, dic etc. My question is:

>

>"Is there any immune directive intervention that is useful in this 

>disease in general?" 

>

>He is receiving excellent agressive regular medical management and 

>unfortunately is on a necessary dose of steroids. I'm not aware of 

>any proven cytokine, hematopoetic factor etc that has been shown to 

>improve the underlying immune problem.

>

>You rapid input even to say nothing new is out there would be 

>greatly appreciated.

>

>Andy Saxon, MD

>UCLA

>

>

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-- 


Charlotte Cunningham-Rundles MD PhD
Professor of Medicine, Pediatrics  and Immunobiology
Mount Sinai School of Medicine
1425 Madison Ave, New York 10029
phone 212 659 9268
fax  212 987 5593
Email:  charlotte.cunningham-rundles at mssm.edu