[PAGID] ID diagnosis

[Chinen, Javier]

I have seen a 14 month-old girl with history of recurrent upper respiratoy infections, with one kidney (the other dysplastic detected in utero and not found posnatal), borderline low IgG, normal IgA and IgM, B cells 1% of lymphocytes (repeated and confirmed), CD4 65%, CD8 15%, NK 15%. Total lymphs 3,600/uL. Height 10 percentile, weight 3 percentile. Not dysmorphic. She has an aunt with history of having one kidney and receiving "immunoglobulin shots", and also she had a splenectomy because "it was not working". 
The father of this child is Caucasian and the mother is from Mexico.
I am measuring reponse to vaccines and will follow up B cells
Any suggestion regarding diagnosis is appreciated. Thank you.
Javier

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