[PAGID] CGD pregnancy

[Dr. Esther de Vries]

Dear Jordan Orange,

 

This is not an answer to your question, but this email reminds me of a
question concerning the ESID meeting in October that I still have. Andrew
Cant has contacted you about the title of your talk during the ESID meeting
itself in the NK-cell session. I still haven't had an answer to that from
him or you, and we want to print the 2nd announcement. Can you please send
me the title asap? Thanks very much, Esther de Vries

 

-----Oorspronkelijk bericht-----
Van: pagid-bounces at list.clinimmsoc.org
[mailto:pagid-bounces at list.clinimmsoc.org] Namens Jordan Orange
Verzonden: woensdag 6 februari 2008 6:32
Aan: pagid at list.clinimmsoc.org
Onderwerp: [PAGID] CGD pregnancy

 

Dear Colleagues,

 

I currently have a 27yo patient with autosomal recessive CGD who would like
become pregnant.

 

Does anyone have experience with this situation?

 

I have many concerns.  

 

One small, but practical concern is that both TMP/SMX and itraconazole are
pregnancy category C.  If she were to become pregnant, is there an
acceptable alternative prophylactic regimen which would be safer for the
fetus?  Alternatively, should TMP/SMX and itraconazole be continued?

This patient and her family have an appropriate fear of CGD, as her younger
sister died of fungal pneumonia 3 years ago.

 

Thank you for reading this message and for any advice you might be able to
offer.

 

Best regards,

 

Jordan

 

Jordan Orange MD/PhD

Assistant Professor of Pediatrics

University of Pennsylvania School of Medicine

Children's Hospital of Philadelphia, Division of Immunology

3615 Civic Center Blvd,  ARC-1016H

Philadelphia, PA 19104

(Voice) 267-426-5622

(Fax) 267-426-5727

www.orangelab.org

 

 





 

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