[PAGID] CGD and bladder wall thickening

[Antonio Condino]

We have a good experience in treating these kind of inflammatory situation with
steroids given 4-8 weeks.

No need of invasive procedures.

Keep on regular antibiotics prophylaxis

-- 
Antonio Condino MD PhD
Associate Professor
Department of Immunology
Institute of Biomedical Sciences
University of Sao Paulo
1730 Lineu Prestes Avenue 1730
Sao Paulo - SP. ZIP 05508-900.
Brazil
Tel 55 11 3091-7387
Fax 55 11 3091-7224



Citando Chris Seroogy <cmseroogy at pediatrics.wisc.edu>:


> 

> We have a 4y/o boy with X-linked CGD and a right wall bladder thickening,

> dysuria and hematuria.  Culture negative, ESR normal and afebrile.

> 

> The imaging consisted of U/S and CT with contrast.  It does not have the

> characteristics of a rhabdo and given his age in situ carcinoma is rare.  I

> am inclined to assume this is non-infectious granulomatous disease and treat

> with oral steroids.  His history is notable for gastric antrum granulomas

> this past Fall responsive to oral steroids and aspergillus pneumonia at

> presentation 3 years ago.

> 

> My questions:

> 

> 

> 1. Would people be comfortable with empiric steroid treatment or is the

> risk/invasive nature of cytoscopy with bx/culture warranted?

> 

> 2. Should empiric antibiotics be started?  If so, what regimen?

> 

> Thank you for your thoughts! Chris

> 

> 

> 

> Chris Seroogy, M.D.

> 

> Assistant Professor

> 

> Dept. of Pediatrics

> 

> Mail:  H4/474 CSC, Mailstop 4108

> 

> Shipping:  H4/431 CSC, Mailstop 4108

> 

> 600 Highland Ave.

> 

> Madison, WI  53792

> 

> phone: 608- 263-2652

> 

> fax: 608-265-0164

> 

> 



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