[PAGID] CGD patient

[Antonio Condino]

I would use Infliximab, keep the antibiotics and be aware about previous BCG
immunization.

I do not think IFN-gamma will help the inflammatory bowel disease because it is
a pro-inflammatory cytokine and may worsen bowel inflammation.

-- 
Antonio Condino MD PhD
Associate Professor
Department of Immunology
Institute of Biomedical Sciences
University of Sao Paulo
1730 Lineu Prestes Avenue 1730
Sao Paulo - SP. ZIP 05508-900.
Brazil
Tel 55 11 3091-7387
Fax 55 11 3091-7224



Citando beatriz <beacarvalho at terra.com.br>:


> Dear  All

> 

> My name is Beatriz costa-Carvalho and I work in São Paulo- Brazil

> 

> I have a female patient, 3 years old, with a diagnosis of CGD and is taking

> co-trimoxazol and itraconazol with control of infections.  Five months ago

> she was diagnosed with Crohn disease. Since them she has used prednisona

> (cushing face), mesalazina and imuran.  She looks well but is still

> presenting enterorrhagia.  Does anybody have experience in using infliximab

> for CGD patients? Could IFN-g be useful in this situation?

> 

> I appreciate  suggestions

> 

> Beatriz Tavares Costa Carvalho

> Profa Adjunto da Disciplina de Alergia, 

> Imunologia Clínica e Reumatologia

> Depto Pediatria - UNIFESP-EPM

> Fone: 55740548

> Fax: 55791590

> e-mail: beacarvalho at terra.com.br or 

> beatrizt.dped at epm.br

> www.imunopediatria.org.br



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