[PAGID] Autoimmune neutropenia

[raas0027 at umn.edu]

Chris,

Does he have eosinophilia? Had GI endoscopy with biopsy? I.e. does he have 
a primary eosinophilic disorder, atopic derm AND AI neutropenia (lots of 
bad luck)?

Or is there a unifying thread - your main question.

Theoretically atopic derm can/does result in staph colonization. Combine 
this with the AI neutropenia and could result in this child's clinical 
picture. A simplistic view, but a possibility.

We have a number of children with AI neutropenia and recurrent infection 
who have had significant improvement on prophylactic amoxicillin.

As the evaluation goes on, what about aggressive skin therapy (which you 
are probably doing) and prophylactic antibiotics that cover staph (e.g. 
TMP/SMX)?

Interesing case.  I too, look forward to other's comments.

Regards,

jason

Jason P. Raasch, MD

Midwest Immunology Clinic
2805 Campus Drive, #215
Plymouth, MN 55441

Office: 763.577.0008
FAX: 763.577.0192
raas0027 at umn.edu