[PAGID] Patient with recurrent abscesses
Berger, Melvin
Melvin.Berger at UHhospitals.org
Fri Jul 18 13:46:41 EDT 2008
The infections have never disseminated ? Has she had pneumatoceles ?
I would check mannan binding lectin.
Melvin Berger, M.D., Ph.D.
Professor of Pediatrics and Pathology
Case Western Reserve University
phone 216 844 3237
Director, Jeffrey Modell Center for Primary Immune Deficiencies
Division of Allergy-Immunology
Rainbow, Babies and Children's Hospital
University Hospitals of Cleveland
RB&C Rm 504, MS 6008B
11100 Euclid Ave.
Cleveland, OH 44106
________________________________
From: pagid-bounces at list.clinimmsoc.org on behalf of Fleisher, Thomas (NIH/CC/DLM) [E]
Sent: Fri 7/18/2008 1:29 PM
To: pagid at list.clinimmsoc.org
Subject: Re: [PAGID] Patient with recurrent abscesses
What is her IgE level?
Thomas A. Fleisher, M.D.
Chief, Department of Laboratory Medicine
NIH Clinical Center
tel 301 496-5668
fax 301 402-1612
email tfleishe at mail.nih.gov
________________________________
From: Abraham, Roshini S., Ph.D. [mailto:Abraham.Roshini at mayo.edu]
Sent: Friday, July 18, 2008 1:15 PM
To: pagid at list.clinimmsoc.org
Cc: Rank, Matthew A., M.D.
Subject: [PAGID] Patient with recurrent abscesses
We have a 43 year old woman from the Northwest United States that has had recurrent staphylococcal abscesses (non-MRSA) since age 9. These have been located in her groin, under and on her arms, abdomen, behind her ear and generally develop within 12-24 hours. She has required multiple incision, drainage, and packing procedures and has take prophylactic antibiotics without significantly decreasing the frequency of their occurrence. She is otherwise healthy except for cigarette smoking, peripheral vascular disease, urinary stress incontinence, and irritable bowel syndrome. She denies eczema. Her father, his sisters, and her paternal grandmother all have the same problem though to a lesser degree. Physical exam is notable only for 1 cm pink raised lesions in her groin area, none are actively draining or fluctuant. Her immune testing to date includes normal IgA, IgM, and IgG. She has had a normal oxidative burst test and normal neutrophil chemotaxis. She does not have anemia, thrombocytopenia or neutropenia. Her ALC is also normal. No evidence of respiratory or other infections, lymphadenopathy, malnutrition etc.
We would appreciate your comments and advice.
Mathew A. Rank, MD, Mayo Clinic, Rochester, MN
Roshini S. Abraham
Roshini Sarah Abraham, Ph.D., D(ABMLI)
Consultant, Div. of Clinical Biochemistry & Immunology
Assistant Professor of Medicine & Lab. Medicine & Pathology
Director
Cellular and Molecular Immunology Laboratory
Department of Laboratory Medicine and Pathology
Hilton 210 e
Mayo Clinic
200 1st St SW
Rochester, MN-55905
Ph: 507-266-9292
Ph (Secy): 507-284-4055
Fax: 507-266-4088
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