[PAGID] lymphopenia

[doctorjlcj at aol.com]

Richard,



Is there anything to suggest a 22q11 deletion?? I ask that given that you can see neurodevelopmental issues in these patients.? I would assume that HIV was screened for.? I would probably send lymphocyte mitogens and antigens (just to be complete), but I would guess these would be normal given he has been clinically well.

Jennifer Caicedo, M.D.
Charlotte


-----Original Message-----
From: Richard L. Wasserman <rich.wasserman at dallasallergy.net>
To: PAGID <pagid at list.clinimmsoc.org>
Sent: Mon, 5 Jan 2009 9:51 pm
Subject: [PAGID] lymphopenia



A 13-year-old boy was referred to heme/onc for evaluation of leukopenia of several years duration. He has no significant infections by history. He has been treated for neuropsychiatic problems with trileptal, welbutrin, Zoloft, Depakote and Concerta. At this time he only takes Concerta and has not had any other medication in more than six months.?
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Physical examination was normal.?
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Over the past five years lymphocyte counts have ranged from 500 to 1200. Most recently, B cell and NK cell number were normal; CD 4 was 300 and CD8 250.?
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Does he need additional evaluation for this laboratory abnormality with no clinical correlate??
Richard L. Wasserman, MD,PhD?
Dallas?

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