[PAGID] lymphopenia

[Richard L. Wasserman]

Thanks for the thoughts. He is not delayed but has had anxiety and 
depression. There are no other findings suggestive of 22q-
Richard

doctorjlcj at aol.com wrote:

> Richard,

>  

> Is there anything to suggest a 22q11 deletion?  I ask that given that 

> you can see neurodevelopmental issues in these patients.  I would 

> assume that HIV was screened for.  I would probably send lymphocyte 

> mitogens and antigens (just to be complete), but I would guess these 

> would be normal given he has been clinically well.

>

> Jennifer Caicedo, M.D.

> Charlotte

>

>

> -----Original Message-----

> From: Richard L. Wasserman <rich.wasserman at dallasallergy.net>

> To: PAGID <pagid at list.clinimmsoc.org>

> Sent: Mon, 5 Jan 2009 9:51 pm

> Subject: [PAGID] lymphopenia

>

> A 13-year-old boy was referred to heme/onc for evaluation of 

> leukopenia of several years duration. He has no significant infections 

> by history. He has been treated for neuropsychiatic problems with 

> trileptal, welbutrin, Zoloft, Depakote and Concerta. At this time he 

> only takes Concerta and has not had any other medication in more than 

> six months. 

>  

> Physical examination was normal. 

>  

> Over the past five years lymphocyte counts have ranged from 500 to 

> 1200. Most recently, B cell and NK cell number were normal; CD 4 was 

> 300 and CD8 250. 

>  

> Does he need additional evaluation for this laboratory abnormality 

> with no clinical correlate? 

> Richard L. Wasserman, MD,PhD 

> Dallas 

>

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