[PAGID] Use of Rituximab in opsoclonus-myoclonus syndrome

[Eleonora Gambineri]

Dear all,

I was asked from the neurology department of my hospital to give an  
opinion regarding treatment with Rituximab in opsoclonus-myoclonus  
syndrome. I have checked in the literature and there are few reports  
describing a beneficial effect of Rituximab in combination with IVIG.  
Although there is no clear indication on how to perform this  
treatment. Usually Rituximab is given once a week for 4 weeks,  
sometime is given for 4 weeks but not always IVIG are started right  
after and are not given monthly as in hypo/agammaglobulinemia? When  
would you start IVIG?

Any thoughts or suggestions will be kindly appreciated.

Best wishes,
Eleonora

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Dott.ssa Eleonora Gambineri
Ricercatore Universitario
Universita' degli Studi di Firenze
Dipartimento di Pediatria-Ospedale Pediatrico "Anna Meyer"
Viale Gaetano Pieraccini, 24
50139 FIRENZE
Tel 055 5662405 (ufficio)
        055 5662464 (lab)
Fax 055 4221012
e-mail: eleonora.gambineri at unifi.it; e.gambineri at meyer.it

Eleonora Gambineri, MD
Researcher/Assistant Professor
University of Florence
Department of Pediatrics-"Anna Meyer" Children's Hospital
Viale Gaetano Pieraccini, 24
50139 FIRENZE
ITALY
Tel +39 055 5662405 (office)
        +39 055 5662464 (lab)
Fax +39 055 4221012
e-mail: eleonora.gambineri at unifi.it; e.gambineri at meyer.it
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