[PAGID] Use of Rituximab in opsoclonus-myoclonus syndrome

[Renner, Eleonore Dr.]

Hi Ele, 
cc'ed Dr. Annette Jansson one of your attendings in regards to this
question who is running clinical studies on Rituximab in our PIDD
clinic. 
She is out off office this week but may be able to check her email. 
Best wishes from Munich, 
Ellen

________________________________

Von: pagid-bounces at list.clinimmsoc.org
[mailto:pagid-bounces at list.clinimmsoc.org] Im Auftrag von Eleonora
Gambineri
Gesendet: Montag, 2. Februar 2009 10:22
An: pagid at list.clinimmsoc.org
Betreff: [PAGID] Use of Rituximab in opsoclonus-myoclonus syndrome


Dear all, 

I was asked from the neurology department of my hospital to give an
opinion regarding treatment with Rituximab in opsoclonus-myoclonus
syndrome. I have checked in the literature and there are few reports
describing a beneficial effect of Rituximab in combination with IVIG.
Although there is no clear indication on how to perform this treatment.
Usually Rituximab is given once a week for 4 weeks, sometime is given
for 4 weeks but not always IVIG are started right after and are not
given monthly as in hypo/agammaglobulinemia? When would you start IVIG?

Any thoughts or suggestions will be kindly appreciated. 

Best wishes,
Eleonora

*******************************************************************
Dott.ssa Eleonora Gambineri
Ricercatore Universitario
Universita' degli Studi di Firenze
Dipartimento di Pediatria-Ospedale Pediatrico "Anna Meyer"
Viale Gaetano Pieraccini, 24
50139 FIRENZE
Tel 055 5662405 (ufficio)
       055 5662464 (lab)
Fax 055 4221012
e-mail: eleonora.gambineri at unifi.it; e.gambineri at meyer.it

Eleonora Gambineri, MD
Researcher/Assistant Professor
University of Florence
Department of Pediatrics-"Anna Meyer" Children's Hospital
Viale Gaetano Pieraccini, 24
50139 FIRENZE
ITALY
Tel +39 055 5662405 (office)
       +39 055 5662464 (lab)
Fax +39 055 4221012
e-mail: eleonora.gambineri at unifi.it; e.gambineri at meyer.it
********************************************************************





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