[PAGID] Use of Rituximab in opsoclonus-myoclonus syndrome

[Nicholas Rider]

Correction, Dr. Pranzatelli's phone number is 217-545-7635.

Thanks,

Nick

Nicholas L. Rider, D.O.
Clinic for Special Children
535 Bunker Hill Road
Strasburg, PA 17579
Ph:  717-687-9407
Fx:   717-687-9237
nrider at clinicforspecialchildren.org



On Feb 2, 2009, at 7:28 AM, Nicholas Rider wrote:


> Dear Eleonora,

>

> We currently care for a 2 year old with OMS.  She presented 6 months  

> ago with disabling eye movements causing regression of her motor  

> development and she could no longer walk.  We treated her with a  

> combination of ACTH, Rituximab and IVIG/SqIG.  She is now walking  

> again and has few signs of OMS.  Upon making the diagnosis, we  

> contacted Dr. Michael Pranzatelli (pranzatelli at siumed.edu;  

> 215-545-7635) of Southern Illinois University School of Medicine; he  

> follows a large cohort of patients with this disorder and has  

> created a treatment protocol for OMS.

>

> I hope this is helpful to you and your patient.

>

> Best Wishes,

>

> Nick

>

> Nicholas L. Rider, D.O.

> Clinic for Special Children

> 535 Bunker Hill Road

> Strasburg, PA 17579

> Ph:  717-687-9407

> Fx:   717-687-9237

> nrider at clinicforspecialchildren.org

>

>

>

> On Feb 2, 2009, at 4:22 AM, Eleonora Gambineri wrote:

>

>> Dear all,

>>

>> I was asked from the neurology department of my hospital to give an  

>> opinion regarding treatment with Rituximab in opsoclonus-myoclonus  

>> syndrome. I have checked in the literature and there are few  

>> reports describing a beneficial effect of Rituximab in combination  

>> with IVIG. Although there is no clear indication on how to perform  

>> this treatment. Usually Rituximab is given once a week for 4 weeks,  

>> sometime is given for 4 weeks but not always IVIG are started right  

>> after and are not given monthly as in hypo/agammaglobulinemia? When  

>> would you start IVIG?

>>

>> Any thoughts or suggestions will be kindly appreciated.

>>

>> Best wishes,

>> Eleonora

>>

>> *******************************************************************

>> Dott.ssa Eleonora Gambineri

>> Ricercatore Universitario

>> Universita' degli Studi di Firenze

>> Dipartimento di Pediatria-Ospedale Pediatrico "Anna Meyer"

>> Viale Gaetano Pieraccini, 24

>> 50139 FIRENZE

>> Tel 055 5662405 (ufficio)

>>        055 5662464 (lab)

>> Fax 055 4221012

>> e-mail: eleonora.gambineri at unifi.it; e.gambineri at meyer.it

>>

>> Eleonora Gambineri, MD

>> Researcher/Assistant Professor

>> University of Florence

>> Department of Pediatrics-"Anna Meyer" Children's Hospital

>> Viale Gaetano Pieraccini, 24

>> 50139 FIRENZE

>> ITALY

>> Tel +39 055 5662405 (office)

>>        +39 055 5662464 (lab)

>> Fax +39 055 4221012

>> e-mail: eleonora.gambineri at unifi.it; e.gambineri at meyer.it

>> ********************************************************************

>>

>>

>>

>>

>>

>


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