[PAGID] CGD patient

[Prof. Dr. Antonio Condino Neto]

I agree
-- 
Antonio Condino-Neto, MD, PhD
Professor of Experimental Medicine - Department of Immunology
Institute of Biomedical Sciences - University of São Paulo
1730 Lineu Prestes Avenue, São Paulo - SP. ZIP 05508-000. Brazil
Tel (55) (11) 3091-7387 / Fax (55) (11) 3091-7224



Citando grumach at usp.br:


> Dear

>

>

> I have just diagnosed CGD in a 3 month old male. He had prolonged  

> fever with unknown origin and BCG vaccination was not looking well.  

> He developed seizures and liquor showed about 600 cells,  

> predominantly lymphomono, high protein and low sugar. No positivity  

> was obtained in the cultures (for BCG still going on).

> He received drugs for all possibilities: Amphotericin, Isoniazide,  

> Pirazinamide, ryphampicin, co-trimoxazole and antibiotics. The fever  

> and seizures disapeared after the 3rd day. BCG lesion is still  

> present (same aspect). The cerebrospinal fluid (after 30 days)  

> presents 73 cells, lymphomono, high protein, low glucose and a  

> previous positive ADA.

> I would suggest to change pirazinamide for ethambutol.

> Do you have any suggestion?

>

> Thanks a lot

>

> Best regards

>

> Anete S Grumach, MD, PhD

> Outpatient group of Primary Immunodeficiencies,

> Dept of Dermatology, University of São Paulo

> Dept of Immunization, Adverse Events, Secretary of Health, São Paulo

>

>

>




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