[PAGID] Herpes virus CMI testing

[Berger, Melvin]

I think Cylex might have an assay for lymphocyte activation by CMV they use for monitoring transplant recipients. 
 
Melvin Berger, M.D., Ph.D.
Adjunct Professor of Pediatrics and Pathology
Case Western Reserve University
phone 216 844 3237
 
Director, Jeffrey Modell Center for Primary Immune Deficiencies
Division of Allergy-Immunology
Rainbow, Babies and Children's Hospital
University Hospitals of Cleveland
RB&C Rm 504, MS 6008B
11100 Euclid Ave.
Cleveland, OH 44106

________________________________

From: pagid-bounces at list.clinimmsoc.org on behalf of Saxon, Andy M.D.
Sent: Fri 4/16/2010 10:45 AM
To: 'pagid at list.clinimmsoc.org'
Subject: Re: [PAGID] Herpes virus CMI testing


Thank you Chuck.
 
They have cultured virus from the eye on both CMV eye subjects, one with the highest load ever reported (there are only a dozen or so cases reported).
 
On the Zoster subject, you bet we need to confirm it before going further.  We need to see one of these "episodes' and culture/document virus in lesions.
 
Andy Saxon, 
UCLA.

________________________________

From: pagid-bounces at list.clinimmsoc.org [mailto:pagid-bounces at list.clinimmsoc.org] On Behalf Of Kirkpatrick, Charles
Sent: Friday, April 16, 2010 7:34 AM
To: 'pagid at list.clinimmsoc.org'
Subject: Re: [PAGID] Herpes virus CMI testing



Andy, Myron Levin at the Dept. of Pediatrics at Univ. Colorado Health Sciences Center might be able to help.  He will want confirmation of the virus.  His e-mail is myron.levin at ucdenver.edu

 

Chuck Kirkpatrick

 

From: pagid-bounces at list.clinimmsoc.org [mailto:pagid-bounces at list.clinimmsoc.org] On Behalf Of Saxon, Andy M.D.
Sent: Friday, April 16, 2010 2:18 AM
To: PAGID (pagid at list.clinimmsoc.org)
Subject: [PAGID] Herpes virus CMI testing

 

Our ophthalmologists have a couple of other wise normal patients with isolated CMV anterior chamber of the eye inflammation. While this is well recognized with Herpes I/II virus, it is very rare with CMV.   The patients' have antibody to CMV but we'd like to measure cell mediated immunity to CMV as well.  

 

Does anyone know a lab or group that does measures cell mediated immunity to CMV?'

 

Similarly, I have an elderly otherwise health lady other than slightly low % and # CD8 cells [CD8 12%(16-41), 102 (255-1090] and reported repeated localized Zoster  which is, as usual, not well confirmed in the records. Clearly we need to establish if it is really Zoster as generally these cases turn out not to be and her level of antibody to Zoster. However, in case,

Does anyone know a lab or group that does measures cell mediated immunity to H. zoster?

 

Andy Saxon, MD 

UCLA School of Medicine

 

 

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