[PAGID] primary cilia dyskinesia

[Berger, Melvin]

Richard- By analogy to CF and CGD, I would expect this patient to have elevated total IgG. If her IgG is just "borderline" you might look at specific antibodies against the organisms grown out on cultures obtained by rhinoscopy. If those are "normal" or elevated, I would not think IgG would add much. 
 
Melvin Berger, M.D., Ph.D.
Adjunct Professor of Pediatrics and Pathology
Case Western Reserve University
Cleveland, OH 44106

________________________________

From: pagid-bounces at list.clinimmsoc.org on behalf of Richard Wasserman
Sent: Wed 8/11/2010 5:18 PM
To: PAGID
Subject: [PAGID] primary cilia dyskinesia


I saw a five year old girl with primary cilia dyskinesia who has been managed with nasal hygiene and rotating aerosolized tobramycin and vancomycin but continues to have chronic sinusitis and recurrent bronchitis. She has had one pneumonia in the past year. Any other management suggestions? Has anyone treated such patients with gamma globulin. This patient has had a normal evaluation in the past and has normal isotypes today. Additional studies are pending.
Thanks,
Richard Wasserman
Dallas

-- 
Richard L. Wasserman, MD, PhD
DallasAllergyImmunology
7777 Forest Lane, Suite B-332
Dallas, Texas 75230
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